Zhonggui He Selected Research

Nanoparticle Drug Delivery System

2/2022	Structurally defined tandem-responsive nanoassemblies composed of dipeptide-based photosensitive derivatives and hypoxia-activated camptothecin prodrugs against primary and metastatic breast tumors.
1/2022	Iron ion-coordinated carrier-free supramolecular co-nanoassemblies of dual DNA topoisomerase-targeting inhibitors for tumor suppression.
11/2021	Smart Nanogatekeepers for Tumor Theranostics.
11/2020	Trisulfide bond-mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity.
1/2016	Self-Assembled Redox Dual-Responsive Prodrug-Nanosystem Formed by Single Thioether-Bridged Paclitaxel-Fatty Acid Conjugate for Cancer Chemotherapy.

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Zhonggui He Research Topics

Disease

121	Neoplasms (Cancer) 06/2022 - 11/2009
25	Breast Neoplasms (Breast Cancer) 02/2022 - 11/2009
17	Neoplasm Metastasis (Metastasis) 04/2022 - 01/2017
7	Hypoxia (Hypoxemia) 03/2022 - 07/2017
3	Hemorrhage 03/2022 - 09/2014
3	Circulating Neoplastic Cells 10/2021 - 01/2019
3	Hypertension (High Blood Pressure) 09/2021 - 12/2009
3	Cardiotoxicity 01/2021 - 05/2020
3	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2018
2	Colonic Neoplasms (Colon Cancer) 06/2022 - 11/2017
2	Melanoma (Melanoma, Malignant) 01/2022 - 12/2021
2	Thrombosis (Thrombus) 01/2022 - 10/2020
2	Inflammation (Inflammations) 01/2022 - 03/2018
2	Rheumatoid Arthritis 01/2022 - 11/2021
2	Lung Neoplasms (Lung Cancer) 12/2021 - 01/2017
2	Carcinoma (Carcinomatosis) 05/2020 - 08/2014
2	Glioma (Gliomas) 12/2018 - 05/2016
2	Liver Neoplasms (Liver Cancer) 12/2016 - 09/2016

Drug/Important Bio-Agent (IBA)

49	Pharmaceutical PreparationsIBA 03/2022 - 09/2003
44	ProdrugsIBA 03/2022 - 11/2014
19	Liposomes (Liposome)IBA 03/2022 - 05/2016
16	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 05/2014
14	DisulfidesIBA 11/2021 - 10/2014
12	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022 - 06/2012
11	Docetaxel (Taxotere)FDA Link 01/2021 - 05/2016
10	1-phenyl-3,3-dimethyltriazene (PDT)IBA 10/2021 - 06/2018
10	AlbuminsIBA 07/2021 - 11/2009
9	Photosensitizing Agents (Photosensitizers)IBA 03/2022 - 09/2018
7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2019
7	Glutathione (Reduced Glutathione)IBA 12/2021 - 01/2019
6	SolutionsIBA 03/2022 - 10/2012
6	Amino Acid Transport Systems (Amino Acid Transporter)IBA 09/2020 - 05/2016
5	Nanoparticle Drug Delivery SystemIBA 02/2022 - 01/2016
5	maleimideIBA 10/2018 - 01/2018
5	Succinic Acid (Succinate)IBA 05/2016 - 06/2012
4	Therapeutic UsesIBA 03/2022 - 08/2014
4	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2022 - 02/2012
4	Sulfides (Thioethers)IBA 01/2020 - 01/2016
4	EnzymesIBA 01/2020 - 01/2018
4	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 06/2012
4	Polymethyl Methacrylate (Sol)IBA 08/2016 - 02/2012
4	tocophersolanIBA 05/2016 - 06/2012
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016 - 12/2010
3	AntigensIBA 06/2022 - 01/2018
3	Biological ProductsIBA 03/2022 - 03/2018
3	pyropheophorbide aIBA 03/2022 - 01/2020
3	CamptothecinIBA 02/2022 - 02/2019
3	DipeptidesIBA 02/2022 - 02/2019
3	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 02/2022 - 02/2019
3	MetalsIBA 01/2022 - 02/2021
3	Cytarabine (Cytosar-U)FDA LinkGeneric 01/2022 - 09/2016
3	Irinotecan (Camptosar)FDA LinkGeneric 10/2021 - 12/2019
3	PlatinumIBA 09/2021 - 11/2015
3	liposomal doxorubicin (Doxil)FDA Link 02/2021 - 05/2020
3	LigandsIBA 09/2020 - 01/2018
3	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 08/2014
3	Amino Acids FDA Link 01/2017 - 12/2016
3	Lysine (L-Lysine)FDA Link 12/2016 - 10/2012
3	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 12/2016 - 06/2012
3	Proteins (Proteins, Gene)FDA Link 08/2016 - 02/2012
3	Tocopherols (Tocopherol)IBA 05/2016 - 10/2012
2	shikoninIBA 06/2022 - 10/2021
2	Peptides (Polypeptides)IBA 02/2022 - 01/2022
2	Immune Checkpoint InhibitorsIBA 01/2022 - 09/2021
2	Coordination ComplexesIBA 01/2022 - 02/2021
2	IronIBA 01/2022 - 11/2021
2	Triglycerides (Triacylglycerol)IBA 11/2021 - 12/2019
2	Drug CombinationsIBA 10/2021 - 01/2019
2	BerberineIBA 10/2021 - 01/2021
2	LipidsIBA 10/2021 - 02/2012
2	Coloring Agents (Dyes)IBA 09/2021 - 10/2018
2	Albumin ReceptorsIBA 07/2021 - 09/2018
2	Albumin-Bound Paclitaxel FDA Link 07/2021 - 11/2009
2	Tyrosine (L-Tyrosine)FDA Link 09/2020 - 12/2019
2	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 01/2020 - 12/2007
2	Cytotoxins (Cytolysins)IBA 01/2020 - 05/2019
2	Surface-Active Agents (Surfactants)IBA 08/2019 - 05/2019
2	Hyaluronic Acid (Hyaluronan)IBA 03/2019 - 05/2014
2	Carnitine (L-Carnitine)FDA LinkGeneric 12/2018 - 11/2017
2	Polylactic Acid-Polyglycolic Acid CopolymerIBA 12/2018 - 11/2017
2	Gemcitabine FDA Link 01/2018 - 01/2018
2	alpha-Tocopherol FDA Link 11/2017 - 10/2014
2	Oleic Acid (Oleate)IBA 11/2017 - 12/2016
2	Ethylene Glycol (Monoethylene Glycol)IBA 10/2014 - 08/2014
2	glucose 6-phosphate(transporter)IBA 05/2014 - 08/2011
2	MicellesIBA 05/2014 - 10/2012

Therapy/Procedure

71	Therapeutics 03/2022 - 09/2010
26	Drug Therapy (Chemotherapy) 01/2022 - 10/2012
12	Immunotherapy 06/2022 - 01/2021
11	Photochemotherapy (Photodynamic Therapy) 10/2021 - 06/2018
6	Lasers (Laser) 02/2022 - 11/2018
6	Phototherapy (Light Therapy) 01/2022 - 09/2018
6	Precision Medicine 11/2021 - 12/2014
3	Combination Drug Therapy (Combination Chemotherapy) 01/2022 - 11/2009
3	Intravenous Administration 07/2021 - 02/2017
3	Transdermal Patch 09/2010 - 12/2009
2	Radiotherapy 01/2022 - 01/2021
2	Injections 01/2022 - 02/2021
2	Intravenous Injections 12/2021 - 01/2021
2	Photothermal Therapy 09/2021 - 01/2019